Behind Active Hydro+™ Technology

Advancing Wellness with Experts in Water Science, Health, and Sustainable Innovation.

Discover the Powerful Health Benefits of Hydrogen Water

  • ✺ Enhanced Hydration

    Hydrogen water absorbs quickly into the body, providing superior hydration at the cellular level, helping you feel replenished faster than regular water.

  • ✺ Sports Recovery

    By reducing oxidative stress and inflammation, hydrogen water aids muscle recovery, alleviates soreness, and accelerates post-workout recovery.

  • ✺ Mental Clarity

    Hydrogen water reduces oxidative stress in the brain, improving focus, cognitive function, and overall mental clarity, helping you stay sharp throughout the day.

  • ✺ Hangover Remedy

    Hydrogen water rehydrates quickly and neutralizes alcohol-induced free radicals, easing hangover symptoms like fatigue and headaches.

  • ✺ Better Energy

    By enhancing cellular efficiency and combating oxidative stress, hydrogen water naturally boosts energy and focus without stimulants.

  • ✺ Antioxidant

    Packed with molecular hydrogen, hydrogen water neutralizes free radicals, reducing aging, inflammation, and supporting overall wellness.

Science at Heart

Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, placebo-controlled trial

Clinical Trial 1



Objective:

To evaluate the effects of the Essentials Powder formula on physical parameters, fatigue, and abdominal issues. A 12-week Randomized, Controlled, Clinical Trial Evaluating the Efficacy of a Dietary Supplement Powder Formula (Daily Ultimate Essentials) in an Adult Population.


Duration:

4 weeks

Participants:

26 healthy adults


Key parameters studied:

  • Levels of inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6).

  • Markers of oxidative stress.

  • Rates of apoptosis in peripheral blood cells.

Outcomes:

Hydrogen-rich water helps reduce inflammation, keeping your body balanced and thriving every day

Please click HERE for full details of Scientific Reports trial

The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial.

Clinical Trial 2



Objective:

To evaluate the safety and effectiveness of hydrogen-rich water (HRW) on aging-related molecular and phenotypic biomarkers in adults aged 70 years and older.


Duration:

6 months

Participants:

40 older adults (20 women)


Key parameters studied:

  • Molecular markers: Telomere length, DNA methylation, antioxidant status, and oxidative stress markers.

  • Brain health: Brain metabolism indices (e.g., choline, NAA, creatine levels).

  • Physical performance: Chair stand test for lower body strength.

  • Subjective measures: General pain, sleep outcomes, and health-related quality of life.

Outcomes:

Drinking hydrogen-rich water helps improve your body’s aging markers, boost brain health, and enhance physical performance, making it a simple way to feel younger and more energized

Please click HERE for full details of Experimental Gerontology trial

Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial

Clinical Trial 3



Objective:

 To evaluate the effects of hydrogen-rich water (HRW) supplementation on muscle recovery in elite fin swimmers after high-intensity training.


Duration:

1 week

Participants:

12 elite Czech fin swimmers


Key parameters studied:

  • Creatine kinase (CK) levels (muscle damage indicator)

  • Muscle soreness (Visual Analogue Scale, VAS)

  • Countermovement jump (CMJ) height (muscle performance)

Outcomes:

HRW supplementation helps you recover faster by reducing muscle soreness, improving muscle performance, and decreasing muscle damage.

Please click HERE for full details of Frontiers in Physiology trial

Clinical Trial 4


Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study


Objective:

To explore the effects of hydrogen-rich water (HRW) on individuals with impaired fasting glucose (IFG), focusing on metabolic parameters and gut microbiota.


Duration:

8 weeks

Participants:

73 patients with impaired fasting glucose (IFG)


Key parameters studied:

  • Fasting blood glucose levels

  • Fatty liver remission

  • Gut microbiota diversity

  • Metabolites.

Outcomes:

Hydrogen-rich water helped improve blood glucose levels, supported fatty liver remission, and balanced gut health in people with impaired fasting glucose, offering a natural solution for better metabolic health.

Please click HERE for full details of National Library of Medicine trial

Clinical Trial 5


Effects of 7-day intake of hydrogen-rich water on physical performance of trained and untrained subjects


Objective:

The study aimed to analyze the ergogenic (performance-enhancing) effect of hydrogen-rich water (HRW) intake for one week on both aerobic and anaerobic performance in trained and untrained individuals.


Duration:

18 days

Participants:

37 volunteers


Key parameters studied:

  • Aerobic performance (measured via VO2max test)

  • Anaerobic performance (measured via maximum anaerobic test, assessing peak and mean power, and fatigue index)

Outcomes:

Seven days of hydrogen-rich water intake boosted anaerobic performance in trained cyclists, increasing power and reducing fatigue, making it an effective hydration strategy for those looking to improve their fitness and endurance.

Please click HERE for full details of Hydrogen Studies trial

Clinical Trial 6


Effect of Hydrogen Water Drinking on Dementia Patients through Mechanism of Oxidative Stress and Immune Redox Balance


Objective:

To investigate the effect of hydrogen water (HW) on dementia patients, particularly its impact on cognitive function, oxidative stress, and immune redox balance.


Duration:

6 months

Participants:

Dementia patients


Key parameters studied:

  • Alzheimer's disease biomarkers (Amyloid β 40, Amyloid β 42, tau)

  • Inflammatory cytokines (IL-1β, IL-6, IL-13, TNF-α, IL-10, IL-4)

  • Th1/Th2 cytokines (IL-2, IFN-γ, IL-12p70, IL-5)

  • Reactive oxygen species (ROS) and nitric oxide (NO) levels

Outcomes:

Drinking hydrogen water for 6 months reduced Alzheimer's biomarkers and inflammation, offering a potential everyday strategy for dementia prevention.

Please click HERE for full details of Hydrogen Studies trial

Clinical Trial 7


Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers


Objective:

To assess the effect of AC-electrolyzed hydrogen-rich water on various diabetes-related serum markers and oxidative DNA damage.


Duration:

8 weeks

Participants:

9 subjects with relatively high blood glucose levels.


Key parameters studied:

  • Urinary 8-hydroxydeoxyguanosine (8-OHdG) levels (marker of oxidative DNA damage)

  • Fasting blood glucose (FBG)

  • 1,5-anhydro-D-glucitol (1,5-AG)

  • HbA1c

  • Fructosamine

Outcomes:

Daily consumption of hydrogen-rich water may help reduce oxidative stress and support better blood sugar control, making it a simple, natural addition to a wellness routine for managing diabetes-related health.

Please click HERE for full details of Medical Gas Research trial

Clinical Trial 8


Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males


Objective:

To investigate whether consuming hydrogen-rich water (HW) reduces oxidative stress and preserves muscle performance during three consecutive days of strenuous exercise.


Participants:

8 healthy, physically active young males

Duration:

1 week


Key parameters studied:

  • Exercise performance: Countermovement jump height, maximal voluntary isometric contraction (MVIC) of knee extensors, and sprint cycling (peak and mean power outputs).

  • Oxidative stress markers:

    • Diacron-reactive oxygen metabolites (d-ROMs)

    • Biological antioxidant potential (BAP)

    • BAP/d-ROMs ratio (index of systemic antioxidant potential).

Outcomes:

Drinking molecular hydrogen-rich water (HW) during consecutive days of strenuous exercise helps maintain antioxidant balance, reduces oxidative stress, and may prevent muscle fatigue, promoting sustained energy and recovery in daily life.

Please click HERE for full details of Medical Gas Research trial

Lab Reaserch


Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress


Objective:

To investigate the therapeutic effects of molecular hydrogen (H₂) on rheumatoid arthritis (RA) by examining its ability to reduce oxidative stress and inhibit inflammation.


Duration:

45 days

Participants:

Male DBA/1J mice for collagen-induced arthritis (CIA) model (n=20).

Human rheumatoid arthritis fibroblast-like synovial cells (RA-FLS) cultured in vitro.


Key parameters studied:

  • Effects of H₂ on oxidative stress markers: superoxide dismutase (SOD), glutathione (GSH), and 8-hydroxy-2'-deoxyguanosine (8-OHdG).

  • Modulation of inflammatory signaling pathways: MAPK, NF-κB, and TGF-β1.

  • Reduction of joint swelling and histopathological changes in CIA mice.

  • Proliferation of RA-FLS cells under oxidative stress.

Outcomes:

Molecular hydrogen may help reduce joint inflammation, alleviate symptoms of rheumatoid arthritis, and support joint health by combating oxidative stress and calming inflammatory pathways, making it a promising natural aid for managing arthritis.

Please click HERE for full details of National Library of Medicine trial

Ready to elevate your hydration?

Discover the benefits of In Lieu’s hydrogen water today.

HAVE MORE QUESTIONS?

    • In Lieu’s hydrogen water offers the experience of premium hydration—smooth, silky, and refreshing, with a subtly sweet aftertaste. Beyond its exceptional taste, it’s enriched with added functional benefits to elevate your hydration experience.

    • Absolutely! Hydrogen water is safe for all age groups and lifestyles, whether you're an athlete, a busy professional, or simply looking to stay hydrated.

    • Hydrogen water is generally free from side effects. However, as with any new product, if you have specific health concerns, consult your healthcare provider.

    • Yes, thanks to our Active Hydro+ Technology, the antioxidant remains effectively dissolved and stable in the water until consumed.

    • No. In Lieu water is 100% natural, enriched with hydrogen, natural electrolytes, and minerals, with no sugars, calories, or artificial additives.

    • No, 0 calaries, 0 sugar, 0 sweeteners.

    • We recommend 3-5 cans per day to experience the optimal benefits of hydrogen water.

  • Hydrogen water is beneficial anytime, but it's particularly effective:

    • Before or after exercise for recovery.

    • In the morning for a refreshing start to the day.

    • During periods of fatigue for a natural energy boost.

    • Hydrogen water complements your daily hydration routine. You can drink it alongside regular water for added benefits.

    • Our hydrogen water is sourced from the pristine Ta-Pieh Mountains, where it naturally flows untouched by civilization. From source to bottling, our process ensures absolute purity. Packaged in eco-friendly aluminum cans, the water is sealed to preserve the molecular hydrogen and maintain its fresh, premium taste.

    • No, thanks to our Active Hydro+ Technology, the benefits of In Lieu’s hydrogen water remain stable regardless of time and temperature, so you can enjoy it at your own pace.

    • Yes, refrigeration is ideal to enjoy the water chilled, but it is not required to maintain the hydrogen content.

    • In Lieu is a proud Hong Kong brand, combining the city’s forward-thinking innovation with nature’s purity. Our hydrogen water is sourced from the pristine Ta-Pieh Mountains and crafted with care to deliver exceptional hydration in eco-friendly aluminum cans.

    • Yes, you can enjoy other In Lieu products alongside our hydrogen water. Our offerings are designed to complement each other, enhancing your overall wellness experience.

  • At In Lieu, we prioritize the highest standards of quality and safety across all aspects of our hydrogen water production:

    • Packaging: We utilize eco-friendly aluminum cans designed to maintain freshness without micro-plastic.

    • Regulatory Compliance: Our products adhere to stringent safety standards, including those set by the U.S. Food and Drug Administration (FDA) and the European Conformity (CE) marking, ensuring compliance with both American and European regulations.

    • Water Safety Standards: We meet and exceed both Hong Kong Drinking Water Standards (HKDWS) and international guidelines, ensuring our water's purity and safety.

    • Production Facility Certification: Our production facilities are certified under the BRCGS Global Standard for Food Safety, a globally recognized certification that guarantees adherence to rigorous food safety and quality requirements.